Description
General Description
DSPE-Biotin is a functional phospholipid derivative containing DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine, C18:0) and a terminal biotin functional group. The biotin moiety enables strong and selective interaction with avidin and streptavidin systems for targeted delivery and bioconjugation applications.
Key Properties
- Biotin-functionalized phospholipid
- Strong affinity toward avidin and streptavidin
- DSPE phospholipid anchor (C18:0)
- Saturated lipid structure for enhanced membrane stability
- Suitable for liposome and nanoparticle functionalization
Applications
- Streptavidin-mediated bioconjugation
- Liposome surface modification
- Lipid nanoparticle engineering
- Targeted drug delivery
- Biomolecule and nanoparticle functionalization
- Diagnostic and biosensor applications
Functional Overview
The DSPE lipid segment provides stable membrane incorporation, while the terminal biotin group enables highly selective binding with streptavidin-containing molecules and systems.
Summary
DSPE-Biotin is a versatile targeting phospholipid widely used in liposome engineering, nanoparticle functionalization, and advanced nanomedicine applications.
