Description
General Description
Thiol-Poly(ε-caprolactone) (PCL-SH) is a thiol-functionalized derivative of poly(ε-caprolactone) (PCL), a biodegradable polyester widely used in biomedical and drug delivery applications. The terminal thiol (-SH) group enables versatile conjugation and crosslinking through thiol-reactive chemistry.
Key Properties
- Thiol-functionalized biodegradable polyester
- Reactive terminal thiol (-SH) group
- Biocompatible and biodegradable polymer
- Suitable for conjugation and crosslinking reactions
- Hydrophobic polyester backbone
Applications
- Thiol-mediated bioconjugation
- Hydrogel and scaffold fabrication
- Drug delivery system development
- Nanoparticle and surface functionalization
- Biomaterial and tissue engineering research
- Crosslinkable polymer system design
Functional Overview
The terminal thiol group enables efficient conjugation with maleimide, vinyl sulfone, and disulfide-reactive compounds, while the PCL backbone provides biodegradability and hydrophobic characteristics suitable for biomedical applications.
