Description
4-Arm PEG-Amine (4-arm PEG-NH₂)
4-Arm PEG-Amine (4-arm PEG-NH₂) is a multi-arm polyethylene glycol (PEG) derivative featuring four reactive primary amine (-NH₂) groups extending from a central pentaerythritol core. This star-shaped architecture provides a high-density functional PEG platform for advanced bioconjugation and cross-linking applications.
Each terminal amine group is highly reactive and can efficiently couple with activated carboxyl groups (such as NHS esters) to form stable amide bonds, making this reagent ideal for multifunctional conjugation strategies.
Key Applications
- Cross-linking of biomolecules and polymers
- Hydrogel and biomaterial network formation
- Drug delivery system design
- Nanoparticle surface functionalization
- Multivalent PEGylation of proteins and peptides
Functional Advantages
- Four reactive amine groups enable high-density conjugation
- Efficient coupling with NHS-activated esters
- Star-shaped structure increases functionality and cross-linking capacity
- Improves solubility and biocompatibility
- Useful for building 3D polymer networks and hydrogels
Summary
4-Arm PEG-Amine is a multifunctional star-shaped PEG reagent designed for high-efficiency cross-linking, biomaterial construction, and advanced drug delivery system engineering.
