ALC-0159

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Product Description

ALC-0159, α-[2-(ditetradecylamino)-2-oxoethyl]-ω-methoxy-poly(oxy-1,2-ethanediyl) is a PEG-lipid conjugate (i.e. PEGylated lipid). Specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG (2,000 Da) (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine (0.05 mg per dose) that contains the active ingredient tozinameran.

Additional information

Package size

100mg, 500mg, 1g

Formal Name              α-[2-(ditetradecylamino)-2-oxoethyl]-ω-methoxy-poly(oxy-1,2-ethanediyl)
CAS Number               1849616-42-7
Molecular Formula    (C2H4O)nC31H63NO2
Purity                            ≥95%
Solubility                     DMF: 10 mg/ml
                                       DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml
                                       DMSO: Slightly Soluble
                                       Ethanol: 1 mg/ml