Description
General Description
OPSS-Poly(L-Arginine), OPSS-Poly-L-Arginine is a functionalized Poly(L-Arginine) derivative containing ortho-pyridyldisulfide (OPSS) groups for thiol-reactive conjugation. The cationic Poly(L-Arginine) backbone enables strong interaction with negatively charged biomolecules, while the OPSS group supports reversible disulfide bond formation with thiol-containing compounds.
Key Properties
- Thiol-reactive OPSS functional group
- Cationic polypeptide polymer
- Supports reversible disulfide conjugation
- Strong interaction with nucleic acids and biomolecules
- Water-soluble functional biomaterial
Applications
- Thiol-mediated bioconjugation
- Gene and nucleic acid delivery
- Redox-responsive drug delivery systems
- Surface modification of nanoparticles and biomaterials
- Hydrogel and polymer functionalization
- Cell-penetrating biomaterial research
Functional Overview
The OPSS group enables selective disulfide exchange reactions with thiol-containing molecules, while the Poly(L-Arginine) backbone supports electrostatic interaction with biological systems and intracellular delivery applications.
Summary
OPSS-Poly(L-Arginine) is a multifunctional cationic polymer widely used in thiol-reactive bioconjugation, gene delivery, and advanced biomaterial engineering applications.
