poly(ε-caprolactone) capped with carboxylic acid (PCL-COOH), is a linear heterofunctional polyester with hydroxyl on one end and carboxyl group on the other.
PCL are a family of biodegradable and bioactive thermoplastic aliphatic polyester. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.
PCL-COOH can be used to prepare nanoparticles, which can be further modified by amine-reactive entities.