- Acetal-Poly-L-glutamic acid (Acetal-pGlu) is a negatively charged synthetic polyamino acid. It is a crystalline solid soluble in water.
- Applications for poly-L-glutamic acid include the conjugation to active molecules for improved activities and the layer-by-layer deposition techniques for surface coating.
- Acetal-functionalized polymers can be easily reduced to aldehyde group using acidic aqueous conditions (pH=2-4). Aldehyde group can selectively react with amine or thiol group in aqueous solution.