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Product Description

DLin-MC3-DMA, or (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate , is one of the most utilized cationic lipids that is used for making Lipid Nano-Particles (LNPs). These lipids, can form nanoparticles that can encapsulate and deliver siRNA, mRNA, DNA or small molecules into the cytoplasm and represent the most advanced delivery platforms for systemic administration of active molecules.  Lipid nanoparticles (LNPs) containing distearoylphosphatidlycholine (DSPC), and ionizableamino-lipids such as dilinoleylmethyl-4-dimethylaminobutyrate (DLin-MC3-DMA) are potent siRNA delivery vehicles in vivo. LNP-siRNA systems optimize to achieve maximum gene silencing potency in hepatocytes following IV administration in mice contain DLin-MC3-DMA (MC3), DSPC, cholesterol and a polyethyleneglycol (PEG)-lipid.

For Research Use Only.

Sold under the Hatch-Waxman exemption (safe harbor exemption)

Additional information

Package size

50mg, 100mg, 1g, 5g

Name:  D-Lin-MC3-DMA
CAS#:   1224606-06-7
Chemical Formula: C43H79NO2
Exact Mass: 641.6111
Molecular Weight: 642.11
Elemental Analysis: C, 80.43; H, 12.40; N, 2.18; O, 4.98
Appearance: Colorless to light yellow liquid
Purity: >95% (or refer to the Certificate of Analysis)