1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phosphatidylcholine with stearoyl (octadecanoyl) acyl groups. It derives from an octadecanoic acid.
Phosphatidylcholine (PC) is generally the most abundant lipid in animal cell membranes providing structural framework. PC is more common in the outer leaflet where it functions as part of the permeability barrier. PC is also the primary substrate of Phospholipase D enzymes which produce the signaling lipids – phosphatidic acid and lysophosphatidic acid.
DSPC is majorly used in the synthesizing liposomes. It is also used in small unilamellar vesicles (SUVs) synthesis.