Maleimide-PEG-Amine (Mal-PEG-NH2) is a linear heterobifunctional PEG reagent with a maleimide and an amine. It is a useful crosslinking reagent with a PEG spacer. Maleimide reacts with thiol, SH, sulfhydryl or mercapto, and amine can react with carboxylic acid or activated NHS ester. MAL-PEG-NH2 can also be used to synthesize PEGylated block copolymers such as PEG-PLL (poly-L-lysine) and PEG-PLGA (poly-L-glutaric acid). It is typically provided as a TFA or HCl salt. Maleimide contains a reactive C=C double bond and is light or oxygen sensitive.
Appearance: Solid powder or chunk, white to off white.
Purity: >90% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 – 4°C for short term (days to weeks) or -20°C for long term (months to years).
Solubility: Soluble in DMSO, dichloromethane, chloroform, acetone, DMF and water.
Stock Solution Storage: 0 – 4°C for short term (days to weeks), or -20°C for long term (months).