Product Description
Methoxy poly(ethylene glycol)-poly(α- carboxyl-ε-caprolactone) (MPEG-PCCL) is a linear amphiphilic block copolymers. One hydrogen at α-position on PCL block is substituted by carboxylic acid. It can be used in preparation of micelles or nanoparticles for drug encapsulation and drug delivery. The pendant -COOH groups on PCL can be used for further modification. For example, drug moieties can be covalently conjugated to the hydrophobic block.
Novel PEO-b-poly(ester) block copolymers with reactive side groups on the polyester block have tremendous potential in the design of optimized carriers for the delivery of various therapeutic agents, as they can assemble to biodegradable nanoscopic micelles with chemically tailorable core structures.
