Methoxy poly(ethylene glycol)-b-Poly(lactide-co-glycolide) amine (mPEG-PLGA-NH2) is a biodegradable a biodegradable amphiphilic block copolymers (ABCs) with terminated -NH2 with PLGA block for drug drug conjugation. PEG is the hydrophilic part and PLGA is the hydrophobic part.
Amphiphilic block copolymers (ABC) consist two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble into micelles when dissolved in an aqueous media.