Azide-PEG-thiol (Azide-PEG-SH, N3-PEG-SH) is a linear heterobifunctional PEG reagent with an azide and a thiol group on the PEG ends. It is a useful crosslinking reagent with a PEG spacer. Azide can be used for molecule conjugation by click chemistry, andthiol can react with -SH or maleimide groups. Azide-PEG-thiol may be used to for bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization.
High quality azide-PEG-thiol (N3-PEG-SH) with a standard quality specification of >90% Substitution.
Heterobifunctional PEG reagents from NSP are generally employed as crosslinking agents or as spacers between two different chemical entities. The PEG moiety in the heterofunctional PEG derivatives provides water solubility, biocompatibility, and flexibility. Applications are especially geared towards the development of antibody drug conjugates.