Acrylate-PEG-amine (ACRL-PEG-NH2) is a linear heterobifunctional PEG reagent with an acrylate and an amine. It is a useful crosslinking reagent with a PEG spacer. Acrylate can polymerize with UV light or radical initiator, and amine can react with carboxylic acid or NHS ester. Acrylate-PEG-Amine may be used to introduce an amine functional group in PEG hydrogel. The product is typically provided in the TFA or HCl salt form.