Poly(L-lactide)-PEG-Maleimide (PLLA-PEG-MAL) is a functional amphiphilic block copolymer to prepare targeted micelles or nanoparticles. Maleimide can conjugate with thiol, SH, sulfhydryl or mercapto group to form a disulfide bond.
Block copolymer micelles are widely used in drug delivery applications. PEG-PLA is a biodegradable polymeric micelle which is used as carriers for hydrophobic drugs like paclitaxel. PEG is the hydrophilic part and PLA is the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.
Appearance: Solid powder or chunk, white to off white.
Purity: >90% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 – 4°C for short term (days to weeks) or -20°C for long term (months to years).
Solubility: Soluble in DMSO, dichloromethane, chloroform, acetone, and DMF
Stock Solution Storage: 0 – 4°C for short term (days to weeks), or -20°C for long term (months).