- Silane-PEG-Maleimide (Silane-PEG-Mal) is a linear heterobifunctional PEG reagent with a maleimide and a silane.
- It is a useful crosslinking reagent with a PEG spacer. Maleimide reacts with thiol, SH, sulfhydryl or mercapto, and silane group can react with glass or other hydroxylated surface or particle.
- It may be used to introduce thiol or cysteine reactive functional group on hydroxylated nanopartilce, microsphere, self-assembled monolayer or metal chips.
- Pegylation can greatly suppress the non-specific binding of charged molecules to the modified surfaces. And they have wide applications for medica device, biomems or biocompatible material development.