Description
General Description
Silane-PEG-NH₂ is a versatile PEG linker designed for surface engineering and biomolecule immobilization. The silane group readily reacts with hydroxylated inorganic materials, forming stable siloxane bonds that anchor the PEG chain to glass, silica nanoparticles, silicon wafers, and metal oxide surfaces.
The terminal amine group can react with activated esters, carboxylic acids, aldehydes, isocyanates, and other amine-reactive compounds, enabling the attachment of proteins, peptides, antibodies, fluorophores, and other biomolecules. The PEG spacer enhances hydrophilicity, flexibility, and biocompatibility while reducing nonspecific adsorption.
Applications
- Surface modification of glass and silica
- Nanoparticle functionalization
- Biosensor fabrication
- Biochip preparation
- Protein immobilization
- Antibody conjugation
- Surface PEGylation
- Biomedical device coatings
- Cell culture substrate modification
- Nanomedicine research
Features and Benefits
- Reactive silane group for stable surface attachment
- Primary amine for versatile conjugation chemistry
- Hydrophilic PEG spacer improves biocompatibility
- Reduces nonspecific surface adsorption
- Suitable for glass, silica, and metal oxide surfaces
- Enables biomolecule immobilization
- Available in multiple PEG molecular weights
- High purity and reproducible performance
