Technical Data
| CAS No. : | 1353016-70-2 |
| Formula : | C19H15NO3 |
| M.W : | 305.33 |
| SMILES Code : | O=C(CCC(O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3 |
| English Name : | Dbco-acid |
| MDL No. : | MFCD28064336 |
| InChI Key : | NDLOVDOICXITOK-UHFFFAOYSA-N |
| Pubchem ID : | 91757805 |
dbco-amine
Price range: $120.00 through $960.00
Description
General Description
dbco-amine TFA is a dibenzocyclooctyne (DBCO) derivative containing a reactive primary amine functional group. The strained cyclooctyne structure enables copper-free click chemistry with azide-containing molecules through strain-promoted azide–alkyne cycloaddition (SPAAC).
Key Properties
- Copper-free click chemistry reagent
- Reactive primary amine functionality
- DBCO moiety enables SPAAC reactions
- Suitable for amide coupling and conjugation chemistry
- Efficient bioorthogonal labeling platform
Applications
- Copper-free click chemistry bioconjugation
- Protein and antibody modification
- Surface functionalization of nanoparticles and biomaterials
- Hydrogel and polymer conjugation
- Drug delivery system development
- Bioorthogonal labeling applications
Functional Overview
The primary amine group enables coupling with activated carboxylic acids and NHS esters to form stable amide bonds, while the DBCO group supports selective copper-free conjugation with azide-functional molecules.
Summary
DBCO-NH₂ is a versatile click chemistry reagent widely used in copper-free bioconjugation, biomolecule modification, and advanced biomaterial engineering applications.
Additional information
| Package Size | 50mg, 100mg, 200mg, 1g, 5g |
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