Description
General Description
DSPE-N₃ is a reactive phospholipid derivative containing DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine, C18:0) and a terminal azide functional group. The azide functionality enables highly selective click chemistry reactions with alkyne-containing molecules for bioconjugation and surface modification applications.
Key Properties
- Azide-functionalized phospholipid
- Suitable for copper-catalyzed and copper-free click chemistry
- DSPE phospholipid anchor (C18:0)
- Saturated lipid structure for enhanced membrane stability
- Suitable for liposome and nanoparticle functionalization
Applications
- Click chemistry conjugation
- Liposome surface modification
- Lipid nanoparticle engineering
- Drug and nucleic acid delivery
- Biomolecule and nanoparticle functionalization
- Nanomedicine and biomaterial applications
Functional Overview
The DSPE lipid segment provides stable membrane incorporation, while the azide group enables selective conjugation with alkyne-containing molecules through click chemistry reactions.
Summary
DSPE-N₃ is a versatile click-reactive phospholipid widely used in liposome engineering, nanoparticle functionalization, and advanced nanomedicine applications.
