PDLLA-PEG-Mal structure

PDLLA-PEG-Biotin

Price range: $300.00 through $1,200.00

PDLLA-PEG-Biotin (Poly(D,L-lactide)-b-Polyethylene Glycol-Biotin) is a tin-free, biodegradable amphiphilic block copolymer consisting of poly(D,L-lactide) (PDLLA) and polyethylene glycol (PEG) terminated with a biotin group. The hydrophobic PDLLA segment enables drug encapsulation and nanoparticle formation, while the hydrophilic PEG segment improves aqueous solubility and biocompatibility. The terminal biotin group allows high-affinity binding to streptavidin and avidin, making PDLLA-PEG-Biotin an excellent material for targeted drug delivery, biofunctionalization, and diagnostic applications.

Product Specifications

Product Name: PDLLA-PEG-Biotin
Polymer Composition: Poly(D,L-lactide)-b-Polyethylene Glycol-Biotin
Molecular Weight: Custom PDLLA and PEG molecular weights available
Functional Groups: Biotin
Appearance: White to off-white solid
Solubility: Water, DMSO, DMF, THF, Chloroform
Storage: -20°C, dry and protected from light
Purity: Typically ≥95%

PDLLA-PEG-biotin structure

SKU: 24000 Categories: , ,

Description

General Description

PDLLA-PEG-Biotin is a tin-free biodegradable block copolymer designed for nanomedicine, drug delivery, and biomaterials research. The amphiphilic structure enables self-assembly into polymeric micelles and nanoparticles with a hydrophobic PDLLA core and a hydrophilic PEG corona.

The biotin functionality enables highly specific interaction with streptavidin and avidin, facilitating the attachment of targeting ligands, proteins, antibodies, imaging probes, and diagnostic agents. PDLLA-PEG-Biotin is widely used for the preparation of functional nanoparticles, targeted delivery systems, and bioactive materials.

Applications

  • Polymeric micelle preparation
  • Nanoparticle fabrication
  • Drug delivery systems
  • Targeted drug delivery
  • Streptavidin-mediated conjugation
  • Antibody immobilization
  • Protein conjugation
  • Diagnostic assay development
  • Nanomedicine research
  • Biomaterials engineering

Features and Benefits

  • Tin-free synthesis process
  • Biodegradable PDLLA block
  • Hydrophilic PEG segment improves biocompatibility
  • Biotin group enables streptavidin/avidin binding
  • Self-assembles into nanoparticles and micelles
  • Suitable for targeted drug delivery
  • High-affinity bio-recognition functionality
  • Available in multiple molecular weight combinations

Additional information

PLA Molecular Weight

1000, 2000, 3000, 4000, 5000, 10000
PEG Molecular Weight

1000, 2000, 3000, 5000
Package size

100mg, 1g

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